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Description of the model used. The ASAP approach was used. This is a statistically designed RBPS program based on the modified Arrhenius equation. The design of the predictive study is based on literature that demonstrates the modeling of observed degradation of solid oral-dosage forms (2,3). Short studies were conducted on open-dish samples of the representative batch of drug product at elevated temperatures over a range of humidity conditions with the goal of reaching the specification limit for the identified SLLA at each condition as detailed as follows. Humidity determines water activity in the drug product and, therefore, can have a significant effect on reaction rates in solid drug products, even for reactions which themselves do not involve water.

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This Ohio-based rapper went Top 40 with his Maybach Music Group debut, "Ohio," which featured guest appearances from Nipsey Hussle, Rick Ross, August Alsina, Ty Dolla Sign, Rashad and De La Soul. PopMatters called it "exactly the album fans could’ve hoped for Stalley to deliver with for his major-label debut" while XXL found it "very refreshing in today’s rap scene."

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